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[DOI] [PMC free article] [PubMed] [Google Scholar] Yue Q, Chen YH, Mulder T, Deese A, Takahashi R, Rudewicz PJ, Reynolds M, Solon E, Hop CE, Wong H, and Khojasteh SC (2011) Absorption, distribution, metabolism, and excretion of [(1)(4)C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening

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