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Timeline expectations based on available research data: Days 1-3 : Telomerase enzyme activation begins, minimal subjective effects reported [1] Days 7-10 : Measurable telomere elongation in laboratory studies, some patients report improved sleep quality [1,4] Days 14-20 : Peak cellular effects observed in research protocols, completion of standard cycle length [1] Months 1-3 : Sustained telomerase activity may persist 4-8 weeks after cycle completion based on cell culture data [1] Months 3-6 : Return to baseline telomerase levels, appropriate timing for next cycle [2] Continuous daily dosing beyond 20 days has not been studied in human subjects and is not recommended in current research protocols [4]

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Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus